Max Planck Institute for Molecular Genetics

Max Planck Institute for Molecular Genetics - Ihnestraße 63-73 - 14195 Berlin - Germany - Phone: (+49 30) 8413 0 - Fax: (+49 30) 8413 1394
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Developmental Genetics


 
Prof. Dr. Bernhard G. Herrmann
Phone (Secretary) (+49 30) 8413 1344
Phone (Office) (+49 30) 8413 1409
Fax (+49 30) 8413 1130

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Publications

J. K. Dale, P. Malapert, J. Chal, G.Vilhais-Neto, M. Maroto, T. Johnson, S. Jayasinghe, P. Trainor, B. Herrmann, and O. Pourquie´. 2006. Oscillations of the Snail Genes in the Presomitic Mesoderm Coordinate Segmental Patterning and Morphogenesis in Vertebrate Somitogenesis. Developmental Cell 10, 355–366

H. Bauer, J. Willert, B. Koschorz  & B.G. Herrmann (2005). The t complex-encoded GTPase-activating protein Tagap1 acts as a transmission ratio distorter in mice. Nature Genetics 37, 969-973

M. Hofmann, K. Schuster-Gossler, M. Watabe-Rudolph, A. Aulehla, B. G. Herrmann
* and A. Gossler* (2004). WNT  signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes Dev 18, 2712-2717 
                                                                      (*corresponding authors)


H. B. Abdelkhalek, A. Beckers, K. Schuster-Gossler, M. N. Pavlova, H. Burkhardt, H. Lickert, J. Rossant, R. Reinhardt, L. C.Schalkwyk, I. Müller,B. G. Herrmann, M. Ceolin, R. Rivera-Pomar, and A. Gossler. (2004) The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation.Genes Dev 18, 1725-1736

A. Aulehla and B. G. Herrmann (2004). Segmentation in vertebrates: clock and gradient finally joined. Genes Dev 18, 2060-2067

A. Aulehla, C. Wehrle, B. Brand-Saberi, R. Kemler, A. Gossler, B. Kanzler, and B. G. Herrmann. (2003) Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev. Cell 4, 395-406

Group 1: Y. Gitton, N. Dahmane, S. Baik, A. Ruiz I Altaba; group 2: L. Neidhardt, M. Scholze, B. G. Herrmann; group 3: P. Kahlem, A. B. Kahla, S. Schrinner, R. Yildirimman, R. Herwig, H. Lehrach, M.-L. Yaspo. (2002) A gene expression map of human chromosome 21 orthologs in the mouse. Nature 420, 586-590

A. Klock & B. G. Herrmann. (2002) Cloning and expression of the mouse dual-specificity MAP kinase phosphatase Mkp3 during mouse embryogenesis. Mech. Development, 116, 243-247

G. Bernier, W. Vukovich, L. Neidhardt, B.G. Herrmann and P. Gruss (2001) Isolation and Characterization of a Downstream Target of Pax6 in the Mammalian Retinal Primordium. Development 128, 3987-3994

K. Wertz and B.G. Herrmann. (2000) Large scale screen for genes involved in gonad development. Mech. Development 98, 51-70

L. Neidhardt, S. Gasca, F. Obermayr, K. Wertz, S. Worpenberg, H. Lehrach and B.G. Herrmann. (2000) Large scale screen for genes controlling embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech. Development 98, 77-93

S. J. Arnold, J. Stappert, A. Bauer, A. Kispert, B. G. Herrmann & R. Kemler. (2000) Brachyury is a target gene of the Wnt/b-catenin signaling pathway. Mech. Development 91, 249-258

M. Leitges, L. Neidhardt, B. Haenig, B.G. Herrmann and A. Kispert. (2000) The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column. Development 127, 2259-2267

B. G. Herrmann, B. Koschorz, K. Wertz, J. McLaughlin & A. Kispert. (1999) A protein kinase encoded by the murine t-complex responder gene causes non-mendelian inheritance. Nature 402, 141-146

A. Kispert, R.J. Stöger, M. Caparros and B.G. Herrmann. (1999) The mouse Rsk3 gene maps to the Leh66 elements carrying the t-complex responder Tcr. Mamm. Genome 10, 794-802

K. Wertz and B.G. Herrmann (1999) Kidney-specific cadherin (cdh16) is expressed in embryonic kidney, lung, and sex ducts. Mech. Development 84, 185-188

Gregorio, C.C., K. Trombitas, T. Centner, B. Kolmerer, G. Stier, K. Kunke, K. Suzuki, F. Obermayr, B.G. Herrmann, H. Granzier, H. Sorimachi and S. Labeit (1998) The NH2 terminus of Titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity. J. Cell Biology 143, 1013-1027

Meier-Ewert, S., J. Lange, H. Gerst, R. Herwig, A. Schmitt, J. Freund, T. Elge, R. Mott, B.G. Herrmann and H. Lehrach (1998) Comparative gene expression profiling by oligonucleotide fingerprinting. Nucleic Acids Res. 26, 2216-2223

C.W. Müller, B.G. Herrmann (1997) Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature 389, 884-888

L.M. Neidhardt, A. Kispert, B.G. Herrmann (1997) A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral culumn, kidney and nervous system. Dev Genes Evol 207, 330-339

B. Kolmerer, N. Olivieri, B.G. Herrmann, S. Labeit (1996) A systematic search of the data bases for sequences homologous to titin/connectin. Advances in Biophysics, Vol 33, 3-11

B. Kolmerer, N. Olivieri, C.C. Witt, B.G. Herrmann, S. Labeit (1996) Genomic organization of M line titin and its tissue-specific expression in two distinct isoforms. J. Mol. Biol. 256, 556-563

D. Clements, H.C. Taylor, B.G. Herrmann, D. Stott (1996) Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation. Mechanisms of Development 56, 139-149

B.G. Herrmann. The Role of Brachyury in the Axial Development and Evolution of Vertebrates, pp. 29-53, in Mammalian Development (ed. Peter Lonai, Harwood Academic Publishers, 1996)

O. Huber, R. Korn, J. McLaughlin, M. Ohsugi, B.G. Herrmann, and R. Kemler (1996) Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mechanisms of Development 59, 3-10







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